Department of Chemical and Biomolecular Engineering
Korea Advanced Institute of Science and Technology


[전산학과] Prof. Luonan Chen, Global Lecture: State-Of-The-Art Technologies in Bioinformatics


ICC Global Lecture: State-Of-The-Art Technologies in Bioinformatics,  5~8 August 2013


Title:    State-Of-The-Art Technologies in Bioinformatics

By:       Prof. Luonan Chen, Institutes for Biological Sciences, Chinese Academy of Sciences

Date:    August 5 (Mon) ~ August 8 (Thu), 2013

Time:   Mon/Tue 10:00-15:00, Wed 10:00-16:00, Thu 09:00-12:00, (lunch break 12:00-13:00)

Venue:              OhSangSu Seminar Room, #4443, 4th Floor, Computer Science Building (E3-1)

Host:    Dept. of Computer Science (Prof. Ho-Jin Choi)


SUMMARY: This global lecture aims to comprehensively cover the contents and the recent topics on theory and computational technologies in bioinformatics, covering general introduction to bioinformatics and research trends/challenges, in particular stressing on the aspects of network and computation with specific biomedical problems and their novel computational methods. Attention will be focused on deriving basic theoretical results, revealing the essential principles of disease development and progression, and identifying network biomarkers for early diagnosis of complex diseases, based on network and informatics theory. Graduate students in Computer Science, Electrical Engineering, and Biological Sciences are mostly welcome.

Day 1 (Monday, Aug 5, 10:00-12:00, 13:00-15:00)

  • Basic concepts in bioinformatics
  • Data mining and machine learning problems from high throughput data
  • Sequence analysis of biological data
  • Phylogenetic analysis and evolution

Day 2 (Tuesday, Aug 6, 10:00-12:00, 13:00-15:00)

  • Basic concepts for network
  • Constructing gene networks from gene expression data
  • Inferring protein-protein interaction network
  • Analyzing structure of biological networks

Day 3 (Wednesday, Aug 7, 10:00-12:00, 13:00-16:00)

  • Analyzing sudden deterioration and phase shift for complex diseases
  • Molecular biomarkers from high throughput data
  • Dynamical network biomarkers for complex diseases
  • Detecting early-warning signals for sudden deterioration of complex diseases

Day 4 (Thursday, Aug 8, 09:00-12:00)

  • Network ontology analysis and its application to complex diseases
  • TF activity network and its applications to type-2 diabetes
  • Identifying dysfunctional modules and disease genes in congenital heart disease
  • Identifying disease genes and module biomarkers with differential interactions for gastric cancer



BIO: Prof. Luonan Chen received M.E. and Ph.D. in the electrical engineering, from Tohoku University, Japan, in 1988 and 1991, resp. From 1997, he was an associate professor of Osaka Sangyo University, then a full Professor. Since 2010, he has been an Executive Director and Professor at Key Laboratory of Systems Biology, Chinese Academy of Sciences, and also a research professor at Tokyo Univ. He was the founding director of Institute of Systems Biology, Shanghai University, and serves as Chair of Technical Committee of Systems Biology at IEEE SMC Society, and is also the founding president of Computational Systems Biology Society of ORS China. His fields of interest are systems biology, bioinformatics, and nonlinear dynamics. He serves as editor or editorial board member for many systems biology related journals, e.g. BMC Systems Biology, IEEE/ACM Trans. on Computational Biology and  Bioinformatics,  J. Royal Society Interface,  Journal of  Molecular  Cell  Biology, IET Systems Biology, Journal of Theoretical Biology, Mathematical Biosciences, Int. J. of Systems and Synthetic Biology, Frontiers in Systems Physiology, and J. of Systems Science and Complexity. In recent five years, he published over 100 journal papers and two monographs (books) in the area of systems biology.



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