A Highly Sensitive Molecular Detection Platform for Robust and Facile Diagnosis of Middle East Respiratory Syndrome (MERS) Corona Virus
Author : Il Young Jung, Jae Bem You, Bo Ram Choi, Ji Su Kim, Hyun Kyung Lee, Bora Jang, Han Saem Jeong, Kyuri Lee, Sung Gap Im*, Hyukjin Lee*
Journal : Advanced Healthcare Materials 2016, 5, 2168-2173
In this work, we demonstrate a definitive molecular diagnosis platform (DhITACT-TR) for rapid and accurate detection of MERS coronavirus. DhITACT-TR offers a robust diagnosis of target RNA pathogens in pseudo-serum specimens with minimum liquid handling as compared to conventional PCR analysis. In addition, a definitive diagnostic result can be achieved within 30 min by an optical detection.