Department of Chemical and Biomolecular Engineering
Korea Advanced Institute of Science and Technology

Recent Achievements


[Inside Front Cover] Metal ion triggers for reversible switching of DNA polymerase

Title: Metal ion triggers for reversible switching of DNA polymerase

Authors: Ki Soo Park, Chang Yeol Lee, and Hyun Gyu Park 
Journal: Chemical Communications
Page: Vol. 52, page 4868-4871 (April, 2016) 
[Abstract] We herein develop a new strategy that modulates DNA polymerase activity in a reversible and switchable manner by using the novel interactions between DNA bases and metal ions (T–Hg2+–T and C–Ag+–C) inside a DNA aptamer capable of inhibiting DNA polymerase





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