Department of Chemical and Biomolecular Engineering
Korea Advanced Institute of Science and Technology

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Front Cover]Simple and Universal Platform for Logic Gate Operations Based on Molecular Beacon Probes


Simple and Universal Platform for Logic Gate Operations Based on Molecular Beacon Probes (Small 14/2012

Ki Soo Park, Myung Wan Seo, Cheulhee Jung, Joon Young Lee, Hyun Gyu Park

Article first published online: 13 JUL 2012

DOI: 10.1002/smll.201290077

The cover picture illustrates how the hairpin-structured molecular beacon probe interacts with DNA input and generates a high fluorescence signal through a sequencespecific hybridization, as demonstrated by H. G. Park and co-workers on page 2203. By employing this molecular beacon probe as a basic work unit and rationally designing a series of DNA inputs, a new universal platform technology for molecular logic gates is demonstrated, which achieves not only a complete set of two-input logic gates, but also gate wiring in multilevel circuits and the reversible modulation of logic gates. This work holds great promise for applications in molecular computing and bioelectronics.


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등록일2012-07-17

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