Department of Chemical and Biomolecular Engineering
Korea Advanced Institute of Science and Technology

Recent Achievements

사진제목
Microbial production of short-chain alkanes Yong Jun Choi & Sang Yup Lee Nature Volume:502,Pages:571–574Date published:(24 October 2013)DOI:doi:10.1038/nature12536 Increasing concerns about limited fossil fuels and global environmental problems have focused attention on the need to develop sustainable biofuels from renewable resources. Although microbial production of diesel...
Title: Synthesis of a 3D graphite microball using a microfluidic droplet generator and its polymer composite with core–shell structure Author: Dong Ju Han, Jae Hwan Jung, Jong Seob Choi, Yong Tae Kim and Tae Seok Seo Journal : Lab on a Chip 2013,13, 4006 Lab Chip, 2013,13, 4006-4010 DOI: 10.1039/C3LC50838B ABSTRACT Spherical 3D graphite microballs (3D GMs) and their nanohybri...
Design and use of synthetic regulatory small RNAs to control gene expression in Escherichia coli Seung Min Yoo,1, 2 Dokyun Na1, 2, 3 & Sang Yup Lee1 Journal name:Nature Protocols Volume:8, Pages: 1694–1707 Year published:(2013)DOI: doi:10.1038/nprot.2013.105 Published online 08 August 2013 Abstract Gene knockout experiments are often essential in functional genomics and metabolic...
Abstract: Pristine graphene quantum dots and graphene oxide quantum dots are synthesized by chemical exfoliation from graphite nanoparticles with high uniformity in terms of shape (circle), size (less than 4 nm), and thickness (monolayer). The origin of the blue and green photoluminescence of GQDs and GOQDs is attributed to intrinsic and extrinsic energy states, respectively. Further d...
ABSTRACT: Fumaric acid is a naturally occurring organic acid that is an intermediate of the tricarboxylic acid cycle. Fungal species belonging to Rhizopus have traditionally been employed for the production of fumaric acid. In this study, Escherichia coli was metabolically engineered for the production of fumaric acid under aerobic condition. For the aerobic production of fumaric acid, t...
Multicolor patterning using holographic woodpile photonic crystals at visible wavelengths Sung-Gyu Park*a and   Seung-Man Yang*a   Nanoscale, 2013,5, 4110-4113 DOI: 10.1039/C3NR00644A Received 05 Feb 2013, Accepted 15 Mar 2013First published online 19 Mar 2013 Abstract High-quality woodpile structures with photonic band gaps in the visible wavelength ...
   Metabolic engineering of Escherichia coli using synthetic small regulatory RNAs Dokyun Na,1, 2 Seung Min Yoo,1, 2 Hannah Chung,1 Hyegwon Park,1 Jin Hwan Park1, 2 & Sang Yup Lee Nature BiotechnologyYear published:(2013)DOI:doi:10.1038/nbt.2461Received17 January 2012 Accepted22 November 2012 Published online20 January 2013 Small regulatory RNAs (...
Rational Design of Escherichia coli for l-Isoleucine Production Jin Hwan Park , Jae Eun Oh , Kwang Ho Lee , Ji Young Kim , and Sang Yup Lee   ABSTRACT   Metabolic engineering of Escherichia coli was performed to construct a 100% rationally engineered strain capable of overproducing l-isoleucine, an important branched-chain amino acid. The thrABC (encoding l-threon...
An integrated allele-specific polymerase chain reaction-microarray chip for multiplex single nucleotide polymorphism typing Jong Young Choi ,  Yong Tae Kim ,  Ju-Young Byun ,  Jinwoo Ahn ,  Soyi Chung ,  Dae-Gab Gweon ,  Min-Gon Kim and Tae Seok Seo ABSTRACT An integrated allele-specific polymerase chain reaction (AS PCR) and microarray chip h...
Elaborate Design Strategies Toward Novel Microcarriers for Controlled Encapsulation and Release Tae Soup Shim, Shin-Hyun Kim,Seung-Man Yang Article first published online: 7 NOV 2012 DOI: 10.1002/ppsc.201200044 Abstract Microencapsulation and the controlled release of bioactive agents have long been investigated and exploited to both improve the fundamental unders...

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