Our laboratory pursues the fusion of NT, BT, and Lab-on-a-chip technology to create a miniaturized comprehensive microsystem, an advanced nanodevice, an integrated cell-based assay and a portable nanomaterial-based biosensor with high-throughput capability, high sensitivity, and high functionality to be applied for point-of-care genetic analysis, U-healthcare and biomedical diagnostics.
1. Integrated Portable Genetic Analyzer
We are developing a fully integrated genetic analysis microdevice for point-of-care DNA testing, food safety monitoring, pathogenic bacteria & virus detection, and forensic human identification for a crime scene investigation. By combining a nucleic acid engineering technique, MEMS technology and microfluidics platform, we are mainly focusing on a micro total analysis system (µTAS) such as a micro-PCR-capillary electro phoresis (Micro-PCR-CE) system and a centrifugal microfluidic platform.
2. Miniaturized Cell Analysis Microsystem
Microfluidic cell chip can provide an unprecedented cell analysis platform in terms of high-throughput capability, single cell manipulation, and in vivo-like biomimetic environments. We are constructing a variety of cell chips with an aim of cancer diagnostics especially circulating tumor cell, organ-on-a-chip, HTP screening of microalgae culture for biofuel production, and single cell based bioassay.
3. Integrated NanoBiosensor
Graphene, fluorescent nanoprobes, metal nanocrystals and organic/inorganic particles have represent extraordinary optical and electrical properties, which widely be applied in the fields of nanosensors and nanoelectronics. We focus on the development of graphene based optical and electrochemical biosensors for sensitive pathogen, heavy metal detection, graphene based memory thin film transistors for flexible display device, graphene/catalyst, and unique graphene/nanoparticle composites.
4. Droplet based MicroNano Synthetic System
Droplet-based microfluidics offers homogenous nanoliter scale reactors in which a variety of unique nanomaterials can be synthesized. We are using the microfluidic droplets to produce uniform biogenic nanoparticles, 3D graphene structure, polymer nanocomposites, and nanocrystals to be applied for sensors, diagnostics, and electronics.